Crain’s Chicago Names Uptake to 2021 Most Innovative Companies List

Recognized for industrial intelligence software and 40+ U.S. patents, Uptake ranks #6 on the tenth annual list

CHICAGO — October 25, 2021 — Uptake has been named to the Crain’s Chicago Business Most Innovative Companies List for a second consecutive year. Based on an independent evaluation of patent output and quality, Uptake placed among the top companies in the Chicagoland area conducting research and development. The company was granted 16 U.S. patents in 2020, many of which leverage data science to improve asset performance, risk mitigation, and enhance environmental, social, and corporate governance (ESG) initiatives in asset-intensive industries.

“Uptake takes an industrial approach to data science, and our patents reflect that. The insights our customers are using each day are being powered by the innovation in Industrial AI and ML from the team,” shared Kayne Grau, CEO, Uptake. “That data science framework and tooling are central to our ability to better serve our customers and their equipment, and the people and communities who depend on them.”

Mark Botticelli, Uptake’s CTO, added: “Uptake has primed itself on research and development in data science as it defines the industrial intelligence arena. It’s exciting to see the work of our data scientists and engineers light up for users in our software, and that our focused investment in AI, ML, and other emerging technologies in the industrial space is supporting better outcomes for customers.”

The recognition from Crain’s Chicago comes as Uptake recently announced that it appointed Kayne Grau as CEO and expanded its leadership team.


Uptake is the industrial intelligence system, providing actionable insight for operators across a variety of industries. Uptake gives all departments — maintenance, reliability, operations, and financial teams — a single, shared, and contextualized view of every operational asset and interaction that affects performance. Driven by powerful data science models and cloud computing, Uptake’s products deliver actionable insights that predict and prevent asset failure, increase compliance with ESG initiatives, mitigate catastrophic risk, optimize maintenance strategy, reduce repair costs, enhance productivity, and ensure operator safety. With 40+ patents and recognized for leadership in Industrial AI by Gartner, the World Economic Forum, CNBC, and Forbes, Uptake is headquartered in Chicago with a presence in Canada, South America, Europe, India, and Australia. To stay up-to-date on what we’re doing, visit us at and follow us on Twitter and LinkedIn.